China Reports Successful Human Trial of Lab-Grown Lung Tissue Tra...

Scientists at the Tongji Medical College in Wuhan, China published results confirming the world first successful transplantation of bioengineered lung tissue grown from a patient own stem cells into a human recipient, with six-month follow-up data showing 78% lung function recovery compared to 42% for conventional donor lung transplants. The lung scaffold was created by seeding a decellularised donor lung matrix with induced pluripotent stem cells derived from the recipient blood sample, eliminating the risk of immune rejection that requires lifelong immunosuppressive drugs in conventional transplants. China National Health Commission has approved a 50-patient expanded trial at three centres. India National Organ and Tissue Transplant Organisation has initiated a memorandum of understanding with Tongji Medical College to observe and participate in the next trial phase.